Egg Freezing

Egg freezing, also known as mature oocyte cryopreservation, is a method used to save women’s ability to get pregnant in the future.

Eggs harvested from your ovaries are frozen unfertilized and stored for later use. A frozen egg can be thawed, combined with sperm in a lab and implanted in your uterus (in vitro fertilization).

Your doctor can help you understand how egg freezing works, the potential risks and whether this method of fertility preservation is right for you based on your needs and reproductive history.

Why it’s done

Egg freezing might be an option if you’re not ready to become pregnant now but want to try to make sure you can get pregnant later.

Unlike with fertilized egg freezing (embryo cryopreservation), egg freezing doesn’t require sperm because the eggs aren’t fertilized before they’re frozen. Just as with embryo freezing, however, you’ll need to use fertility drugs to make you ovulate so that you’ll produce multiple eggs for retrieval.

You might consider egg freezing if:

  • You have a condition or circumstance that can affect your fertility. These might include sickle cell anemia, autoimmune diseases such as lupus, and gender diversity, such as being transgender.
  • You need treatment for cancer or another illness that can affect your ability to get pregnant. Certain medical treatments — such as radiation or chemotherapy — can harm your fertility. Egg freezing before treatment might enable you to have biological children later.
  • You’re undergoing in vitro fertilization. When undergoing in vitro fertilization, some people prefer egg freezing to embryo freezing for religious or ethical reasons.
  • You wish to preserve younger eggs now for future use. Freezing eggs at a younger age might help you get pregnant when you’re ready.

You can use your frozen eggs to try to conceive a child with sperm from a partner or a sperm donor. A donor can be known or anonymous. The embryo can also be implanted in the uterus of another person to carry the pregnancy (gestational carrier).

Risks

Egg freezing carries various risks, including:

  • Conditions related to the use of fertility drugs. Rarely, use of injectable fertility drugs, such as synthetic follicle-stimulating hormone or luteinizing hormone to induce ovulation, can cause your ovaries to become swollen and painful soon after ovulation or egg retrieval (ovarian hyperstimulation syndrome). Signs and symptoms include abdominal pain, bloating, nausea, vomiting and diarrhea. Even rarer is the possibility of developing a more severe form of the syndrome that can be life-threatening.
  • Egg retrieval procedure complications. Rarely, use of an aspirating needle to retrieve eggs causes bleeding, infection or damage to the bowel, bladder or a blood vessel.
  • Emotional risks. Egg freezing can provide hope for a future pregnancy, but there’s no guarantee of success.

If you use your frozen eggs to have a child, the risk of miscarriage will be primarily based on your age at the time your eggs were frozen. Older women have higher miscarriage rates, mainly due to having older eggs.

Research to date hasn’t shown an increase in the risk of birth defects for babies born as a result of egg freezing. However, more research is needed on the safety of egg freezing.

How you prepare

If you’re considering freezing your eggs, look for a fertility clinic with expertise in the field. Experts are commonly known as reproductive endocrinologists.

The Centers for Disease Control and Prevention and the Society for Assisted Reproductive Technology provide information online about U.S. fertility clinics’ pregnancy and live birth rates, although data related to pregnancies using frozen eggs is limited. Keep in mind, however, that a clinic’s success rate depends on many factors, such as the ages of the women it treats.

If the expense of egg freezing concerns you, ask for information about the costs associated with each step of the procedure and the annual storage fees.

Before beginning the egg-freezing process, you’ll likely have some screening blood tests, including:

  • Ovarian reserve testing. To determine the quantity and quality of your eggs, your doctor might test the concentration of follicle-stimulating hormone and estradiol in your blood on day three of your menstrual cycle. Results can help predict how your ovaries will respond to fertility medication.
    Another blood test and an ultrasound of the ovaries might be used to get a more complete picture of ovarian function.
  • Infectious disease screening. You’ll be screened for certain infectious diseases, such as HIV and hepatitis B and C.

What you can expect

Egg freezing has multiple steps — ovarian stimulation, egg retrieval and freezing.

Ovarian stimulation

You’ll take synthetic hormones to stimulate your ovaries to produce multiple eggs — rather than the single egg that typically develops monthly. Medications that might be needed include:

  • Medications for ovarian stimulation. You might inject medication such as follitropin alfa or beta (Follistim AQ, Gonal-f) or menotropins (Menopur).
  • Medications to prevent premature ovulation. Your doctor might prescribe an injectable gonadotropin-releasing hormone agonist such as leuproline acetate (Lupron) or a gonadotropin-releasing hormone antagonist such as cetrorelix (Cetrotide).

During treatment, your doctor will monitor you. You’ll have blood tests to measure your response to ovarian-stimulation medications. Estrogen levels typically increase as follicles develop, and progesterone levels remain low until after ovulation.

Follow-up visits will also include having vaginal ultrasound — a procedure that uses sound waves to create an image of the inside of your ovaries — to monitor the development of fluid-filled sacs where eggs mature (follicles).

When the follicles are ready for egg retrieval — generally after 10 to 14 days — an injection of human chorionic gonadotropin (Pregnyl, Ovidrel) or another medication can help the eggs mature.

Egg retrieval

Egg retrieval is done under sedation, typically in your doctor’s office or a clinic. A common approach is transvaginal ultrasound aspiration, during which an ultrasound probe is inserted into your vagina to identify the follicles.

A needle is then guided through the vagina and into a follicle. A suction device connected to the needle is used to remove the egg from the follicle. Multiple eggs can be removed, and studies show that the more eggs retrieved— up to 15 per cycle — the better the chances of birth.

After egg retrieval, you might have cramping. Feelings of fullness or pressure might continue for weeks because your ovaries remain enlarged.

Freezing

Shortly after your unfertilized eggs are harvested, they’re cooled to subzero temperatures to preserve them for future use. The makeup of an unfertilized egg makes it a bit more difficult to freeze and lead to a successful pregnancy than does the makeup of a fertilized egg (embryo).

The process most commonly used for egg freezing is called vitrification. High concentrations of substances that help prevent ice crystals from forming during the freezing process (cryoprotectants) are used with rapid cooling.

After the procedure

Typically, you can resume normal activities within a week of egg retrieval. Avoid unprotected sex to prevent an unintended pregnancy.

Contact your health care provider if you have:

  • A fever higher than 101.5 F (38.6 C)
  • Severe abdominal pain
  • Weight gain of more than 2 pounds (0.9 kilograms) in 24 hours
  • Heavy vaginal bleeding — filling more than two pads an hour
  • Difficulty urinating

Results

When you want to use your frozen eggs, they’ll be thawed, fertilized with sperm in a lab, and implanted in your or a gestational carrier’s uterus.

Your health care team might recommend using a fertilization technique called intracytoplasmic sperm injection (ICSI). In ICSI, a single healthy sperm is injected directly into each mature egg.

The chances of becoming pregnant after implantation are roughly 30 to 60 percent, depending on your age at the time of egg freezing. The older you are at the time of egg freezing, the lower the likelihood that you’ll have a live birth in the future.

She is not merely a brilliant doctor but she is also a genuine, honest and compassionate human being which is the differentiator between a good doctor and a great one. Strongly recommended.

Shikha Misra

Shikha Misra

4th Avenue

Thanks for Ur love,care n support throughout in my pregnancy. Even I was remembering Ur motherly care at the time of delivery also. U hv been an angel to have me my second child happily n healthily.

Khusboo Arora

Khusboo Arora

12 Main Road

Dr. Shweta Mittal Gupta, a doctor par excellence, a great orator, a wonderful human being and above all my inspiration, my mentor. May God bless her in all her endeavours.

Raman Singla

Raman Singla

23rd Street

Dr.Shweta has been a ray of light in our lives helping us to have the most beautiful gift of life in the form of our baby. Her knowledge and expertise in her field is significant. Apart from being a remarkable gynecologist, she is a wonderful human being supporting her patients with utmost care. I highly recommend Dr.Shweta and her support team.

Swati Shankdhar

Swati Shankdhar

Dr. Shweta Mittal has been really helpful throughout my pregnancy and always there a call away. My sister in law referred me here and I am really satisfied with the care and help she offers. She is really supportive and explains everything nicely whatever we asked her.

Sonam Arya

Sonam Arya

Hi, we are grateful to Dr.Shweta, the whole team works like a good and competent team under the guidance of Dr.Shweta and above all, I always say to her whenever I meet her that “I Love You” my deepest regards to her. I am blessed with a baby girl and wish that one day she will also be Competent, commanding, intelligent and successful like ma’am, thanks to ma’am and every team member.

 Amit Mutreja

 Amit Mutreja

Dr. Shweta Mittal Gupta, a doctor par excellence, a great orator, a wonderful human being and above all my inspiration, my mentor. May God bless her in all her endeavours.

Shubhi Arora

Shubhi Arora

Our journey start from Oct 2018 with Dr shweta Mittal in Sir Ganga Ram hospital. On First met we were get insure that Dr.Shweta Mittal is the only Doctor Who make us happy to get parents. She is very good in nature, soft-spoken, kind hearted person. Now we get a healthy baby by the grace of God and with the bless of Dr Shweta Mittal

Ravi Aggarwal

Ravi Aggarwal

After 6 years of marriage and while we were missing the presence of a child in our life. We were referred by a close friend of us. Who herself was a patient of Dr. Shweta Mittal. Dr. Shweta turned out to be the Angel we were searching for and within 2 months the good news was there.

Balaji Kumar

Balaji Kumar

We had a great experience with Dr. Shweta Mittal Gupta. Her clinical sense, experience and expertise has made us proud parents today. She has guided us very well before and throughtout the pregnancy. Thanks alot ma’m.High regards.

Amit Kumar

Amit Kumar

Shewta Mittal Gupta is a great doctor.She has provided us best treatment.Formulated very good strategy which one was very benefical in long term and in contigency for us.Today we blessed with baby boy just because of Doctor Shewta Mittal Gupta.For us Doctor Shewta Mittal Gupta is the best.She did miracle for us.

Ravi Kumar

Ravi Kumar

Dr Shweta Mittal is a blessing for us, we have met her last year after reading reviews and thats when we figured out that we are in right hands, she listened to us and gave us the comfort we needed. She is very soft spoken and she explains everything in detail where a layman could understand complex procedures of medicine.

DIGVIJAI TRIPATHI

DIGVIJAI TRIPATHI

A very wonderful and an amazing experience I have with my doctor (Dr. Shweta Mittal Gupta) who has given me the best gift of motherhood. Her positive attitude towards the condition of an IVF patient is just unexplainable. Her only word which I had heard from her mouth was (then what)always gave me the positive energy for handling my nine months of pregnancy.

Garima Chhabra

Garima Chhabra

My heartiest and biggest Thanks to Dr Dr shweta mittal ma’am. She vaid for making my journey completely of parenthood. After 7 years of marriage and struggle for parenthood Now I bless to enter motherhood. Just because of Dr shweta mittal ma’am and her advance and Hi_technology I will always be obligated to Dr shweta mittal.

Preeti Khattar

Preeti Khattar

I am very grateful to Dr Shweta Mittal that due to her IVF treatment and guidance, i am now mother of a baby girl. Earlier i was very disappointed but the type of guidance and treatment was given to me by Dr Shweta mittal..this miracle happens. Thankyou vey much doctor.

Shakeel Ahmed

Shakeel Ahmed

Dr. Shweta Mittal Maam is the number one IVF specialist in the country. She is the best most soft spoken out of the world and amazing Doctor of us. I will highly recommend Dr shweta mittal maam to everybody. Thank you so much Dr shweta mittal maam n her ivf team

Kabeer

Kabeer

Today i am very happy i blassed with a baby girl after marriage of 23 year just because of Dr Shweta mittal mam gudience & help.Our journey today complete.She always help in emergency satution she is very good listion .
Once again Thanku very much of Dr shweta Mittal mam & Her IVF team for supporting us every time.

Jeetyendra Negi

Jeetyendra Negi