OVULATION INDUCTION

Ovulation Induction

  • Ovulation induction is a treatment for anovulation (irregular ovulation), an infertility condition in which follicles in a woman’s ovary do not mature and release eggs (ovulate).
  • Anovulation can be caused by certain reproductive disorders such as polycystic ovary syndrome (PCOS), nutritional problems or excessive exercise.
  • Ovulation induction is typically achieved with a variety of medications that stimulate the ovary to produce and release eggs.
  • If the treatment is successful, the woman will ovulate and can become pregnant naturally using intrauterine insemination (IUI) or other fertility treatments.
  • Approximately 25 percent of female infertility cases stem from problems with ovulation, so ovulation induction can be a beneficial and cost-effective first treatment.

What is ovulation induction?

Ovulation induction is the process of using medications to stimulate ovulation in women who have irregular or absent ovulation (anovulation). According to the National Institutes of Health, 25 to 30 percent of women with infertility have problems with ovulation.

Normal ovulation occurs when the ovary releases a mature egg in preparation for that egg to be fertilized. Normal ovulation occurs roughly once every 28 days during a woman’s menstrual cycle. Intervals of 21 to 35 days are considered acceptable and reflective of normal ovulation. If fertilization does not occur, the mature egg and any supplementary tissues are broken down and cleared from the uterus naturally.

When ovulation happens less than once every 35 days or is unpredictable, it is considered to be irregular. When ovulation is completely unpredictable – in interval or duration – it is considered oligoovulation. If it doesn’t occur at all, it is called anovulation. Ovulatory problems impact fertility by taking away the predictability of ovulation and potentially the availability of an egg to be fertilized.

The goal of ovulation induction is to increase a woman’s chances of conceiving a child, either through sexual intercourse or by using intrauterine insemination (IUI) or another fertility treatment. However, when the absence of ovulation is a symptom of another fertility issue, treating the underlying problem can also restore normal ovulation and fertility.

Medications used for ovulation induction

Ovulation induction uses a variety of hormone-based medications to regulate a woman’s reproductive hormones and increase the chances of ovulation. Some of the commonly used medications are:

  • Clomiphen citrate: Stimulates ovulation in women who have normal pituitary (a gland in the brain) hormones but in whom the normal monthly changes in these hormones are not occurring. Most patients know this medication by its brand name Clomid.
  • Aromatase inhibitors: With similar indications as for clomiphene citrate, this type of medication is very effective in patients with PCOS. Most patients know this medication as letrozole or by the brand name Femara.
  • Insulin-sensitizing agents: These are used in some PCOS patients who have evidence of diabetes or prediabetes. Most patients know this medication as metformin.
  • Gonadotropins: Consist of two injectable hormones, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), that encourage egg development and are normally produced by the pituitary gland. Because of how powerfully gonadotropins stimulate egg development, they require more frequent monitoring than clomiphene citrate and letrozole. Risks include multiple pregnancy and ovarian hyperstimulation syndrome (OHSS), in which the ovaries become overstimulated and swollen.

In some cases, treating another condition, such as obesity or hypothyroidism, can jump-start ovulation naturally.

Who could benefit from ovulation induction

Ovulation induction is a common treatment for women with absent or infrequent ovulation. Women with ovulation-interrupting disorders such as PCOS can also benefit from ovulation induction.

Ovulation induction also works in conjunction with in vitro fertilization (IVF) by stimulating multiple mature eggs to release for collection and use in lab fertilization. This is typically called controlled ovarian hyperstimulation.

When determining whether or not to use ovulation induction, physicians usually look at:

  • Disorders that can directly inhibit normal ovulation such as PCOS.
  • A woman’s hormone levels, specifically the presence of FSH), AMH and LH.
  • Disorders can indirectly affect ovulation, such as thyroid disorders, eating disorders and obesity.
  • The amount of exercise a woman does.

For women who continue to experience abnormal ovulation after ovulation induction treatment, physicians can also try superovulation. Superovulation uses the human chorionic gonadotropin hormone to induce the release of potential mature eggs in the follicle.

 Risks and side effects of ovulation induction

Ovulation induction medications can sometimes cause OHSS. The side effects of OHSS range from mild to severe, and usually fade after a few weeks without treatment. They can include:

  • Bloating.
  • Nausea.
  • Headaches.
  • Loss of breath.
  • Hot flashes.
  • Weight gain.
  • Tenderness in the pelvic region.
  • Blurry vision.

The ovarian superovulation treatment can cause multiple eggs to release, increasing the chance of multiple fertilized eggs (embryos) and a high-risk pregnancy.

Benefits of ovulation induction

Ovulation induction is usually one of the first treatments used for infertility because it is noninvasive and relatively low cost compared with other fertility treatments, such as IVF that includes costs of tests, medications, minor procedures and lab work.

For more severe cases of anovulation or other causes of infertility, ovulation induction can also be an effective treatment in conjunction with IVF, intrauterine insemination (IUI) and other holistic treatments.

 

She is not merely a brilliant doctor but she is also a genuine, honest and compassionate human being which is the differentiator between a good doctor and a great one. Strongly recommended.

Shikha Misra

Shikha Misra

4th Avenue

Thanks for Ur love,care n support throughout in my pregnancy. Even I was remembering Ur motherly care at the time of delivery also. U hv been an angel to have me my second child happily n healthily.

Khusboo Arora

Khusboo Arora

12 Main Road

Dr. Shweta Mittal Gupta, a doctor par excellence, a great orator, a wonderful human being and above all my inspiration, my mentor. May God bless her in all her endeavours.

Raman Singla

Raman Singla

23rd Street

Dr.Shweta has been a ray of light in our lives helping us to have the most beautiful gift of life in the form of our baby. Her knowledge and expertise in her field is significant. Apart from being a remarkable gynecologist, she is a wonderful human being supporting her patients with utmost care. I highly recommend Dr.Shweta and her support team.

Swati Shankdhar

Swati Shankdhar

Dr. Shweta Mittal has been really helpful throughout my pregnancy and always there a call away. My sister in law referred me here and I am really satisfied with the care and help she offers. She is really supportive and explains everything nicely whatever we asked her.

Sonam Arya

Sonam Arya

Hi, we are grateful to Dr.Shweta, the whole team works like a good and competent team under the guidance of Dr.Shweta and above all, I always say to her whenever I meet her that “I Love You” my deepest regards to her. I am blessed with a baby girl and wish that one day she will also be Competent, commanding, intelligent and successful like ma’am, thanks to ma’am and every team member.

 Amit Mutreja

 Amit Mutreja

Dr. Shweta Mittal Gupta, a doctor par excellence, a great orator, a wonderful human being and above all my inspiration, my mentor. May God bless her in all her endeavours.

Shubhi Arora

Shubhi Arora

Our journey start from Oct 2018 with Dr shweta Mittal in Sir Ganga Ram hospital. On First met we were get insure that Dr.Shweta Mittal is the only Doctor Who make us happy to get parents. She is very good in nature, soft-spoken, kind hearted person. Now we get a healthy baby by the grace of God and with the bless of Dr Shweta Mittal

Ravi Aggarwal

Ravi Aggarwal

After 6 years of marriage and while we were missing the presence of a child in our life. We were referred by a close friend of us. Who herself was a patient of Dr. Shweta Mittal. Dr. Shweta turned out to be the Angel we were searching for and within 2 months the good news was there.

Balaji Kumar

Balaji Kumar

We had a great experience with Dr. Shweta Mittal Gupta. Her clinical sense, experience and expertise has made us proud parents today. She has guided us very well before and throughtout the pregnancy. Thanks alot ma’m.High regards.

Amit Kumar

Amit Kumar

Shewta Mittal Gupta is a great doctor.She has provided us best treatment.Formulated very good strategy which one was very benefical in long term and in contigency for us.Today we blessed with baby boy just because of Doctor Shewta Mittal Gupta.For us Doctor Shewta Mittal Gupta is the best.She did miracle for us.

Ravi Kumar

Ravi Kumar

Dr Shweta Mittal is a blessing for us, we have met her last year after reading reviews and thats when we figured out that we are in right hands, she listened to us and gave us the comfort we needed. She is very soft spoken and she explains everything in detail where a layman could understand complex procedures of medicine.

DIGVIJAI TRIPATHI

DIGVIJAI TRIPATHI

A very wonderful and an amazing experience I have with my doctor (Dr. Shweta Mittal Gupta) who has given me the best gift of motherhood. Her positive attitude towards the condition of an IVF patient is just unexplainable. Her only word which I had heard from her mouth was (then what)always gave me the positive energy for handling my nine months of pregnancy.

Garima Chhabra

Garima Chhabra

My heartiest and biggest Thanks to Dr Dr shweta mittal ma’am. She vaid for making my journey completely of parenthood. After 7 years of marriage and struggle for parenthood Now I bless to enter motherhood. Just because of Dr shweta mittal ma’am and her advance and Hi_technology I will always be obligated to Dr shweta mittal.

Preeti Khattar

Preeti Khattar

I am very grateful to Dr Shweta Mittal that due to her IVF treatment and guidance, i am now mother of a baby girl. Earlier i was very disappointed but the type of guidance and treatment was given to me by Dr Shweta mittal..this miracle happens. Thankyou vey much doctor.

Shakeel Ahmed

Shakeel Ahmed

Dr. Shweta Mittal Maam is the number one IVF specialist in the country. She is the best most soft spoken out of the world and amazing Doctor of us. I will highly recommend Dr shweta mittal maam to everybody. Thank you so much Dr shweta mittal maam n her ivf team

Kabeer

Kabeer

Today i am very happy i blassed with a baby girl after marriage of 23 year just because of Dr Shweta mittal mam gudience & help.Our journey today complete.She always help in emergency satution she is very good listion .
Once again Thanku very much of Dr shweta Mittal mam & Her IVF team for supporting us every time.

Jeetyendra Negi

Jeetyendra Negi

Subscribe to My Newsletter


Private OPD

Mon-Sat, OPD No.F 45Time: 2-4 pmSir Ganga Ram HospitalRajinder Nagar, New Delhi-110060For appointment:011-42254000 ,011-42251800

Clinic: Unity Health Care clinic (UHC)

Mon - Sat (9 am - 6 pm)7/11, Ground Foor, East Patel Nagar,New Delhi110008For appointment: 8800443314

Teleconsultation & video consultation

Download app My follow up, doctor ID: 70Visit www.sgrh.com